Computational Algorithms for Protein Structures and Interactions

Inria, CNRS, University of Lorraine




Univeristè de Lorraine

About Capsid

The Capsid team develops algorithms and software to help study biological systems and phenomena from a structural point of view. In particular, the team aims to develop algorithms which can facilitate and improve the 3D modeling of large multi-component bio-molecular machines. While the team’s principal activity is algorithm and software development, it also tackles "real-world" biological problems through collaborations with the University of Lorraine and Nancy Hospital, and with other research teams from Inria, CNRS, INRA, INSERM, and international universities.

The team's activities focus on two main themes: computational modeling of protein-protein interactions (protein docking and molecular dynamics simulations), and classifying and mining protein structures and protein interactions (knowledge discovery in biological databases).

The team is common ("Equipe Projet Commun") to the CNRS, Inria, and the University of Lorraine, and is a research node of the Institut Français de Bioinformatique.

Key Words

Structural bioinformatics; protein docking; protein interactions; biological data mining; molecular dynamics; virtual drug screening.


Since March 16, 2020, the Capsid team has been teleworking (intensively!) due to the Covid-19 pandemic.

Marie-Elisa Ruiz-Echartea defended her PhD thesis on 18 December 2019. She left in February 2020 for a post-doc at Kansas University in Ilya Vakser's lab. Good luck to her !

Kamrul Islam joined us as PhD student in November 2019 on a UL PhD thesis contract!

Diego Amaya Ramirez joined us as PhD student in October 2019 on an INRIA-Inserm PhD thesis contract!

Hrishikesh Dhondge and Anna Kravchenko joined us as Marie Sklodowska-Curie PhD students in October 2019 on the European ITN RNAct project!

On September 15, 2019, the Capsid team founder David W Ritchie passed away after a last courageous fight against his cancer. We miss him dearly.

Antoine Moniot and Athénaïs Vaginay joined us as PhD students in October 2018!